Fish (and shellfish) can accumulate extremely high levels of toxins (as much as 9 million times that of the water in which they live) such as PCB's, dioxins, mercury, lead, and arsenic, which can cause health problems ranging from kidney damage and impaired mental development to cancer and even death. Fish oil capsules may also contain harmful contaminants. Omega-3, thought to be helpful in fighting heart disease, can be found in flax and linseed oils and leafy, green vegetables.
Don't mistake Seafood for Healthfood
From the Physician's Committee for Responsible Medicine web site.
Taste of the Ocean

The freshest catch isn't from the sea! Let the fish swim free, but hang on to the taste with these delicious recipes.
Tuna-Safe-Tuna
Why stop at dolphin-safe tuna?